A great many projects at various stages of development are characterized by their goal of forcing greater stem cell activity in old tissues, but without meaningfully addressing the underlying causes of stem cell decline in later life. This sort of research and development operates at the level of proximate causes, adjusting protein levels to change cell behavior. Among the potential therapies I’d place into this category: telomerase gene therapy; GDF11 upregulation; FGF2 inhibition; NAD+ upregulation; and so on. Muscle stem cells known as satellite cells are one of the better studied stem cell populations in this context, and many of the interventions are focused here. Today’s open access research is a representative example, in that the authors describe a portion of the network of genes and proteins
from http://besthealthnews.com/2019/10/targeting-gas1-to-put-muscle-stem-cells-back-to-work-in-old-tissues/?utm_source=rss&utm_medium=rss&utm_campaign=targeting-gas1-to-put-muscle-stem-cells-back-to-work-in-old-tissues
from
https://healthnews010.tumblr.com/post/188141740348
from https://johnher1.blogspot.com/2019/10/targeting-gas1-to-put-muscle-stem-cells.html
from
https://johnher10.tumblr.com/post/188141949247
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